Hypertension, antihypertensive drugs and atherosclerosis.
نویسنده
چکیده
منابع مشابه
THE EFFECT OF ANTIHYPERTENSIVE DRUGS IN THE SUPPRESSION OF ATHEROSCLEROSIS
The present investigation was undertaken to evaluate the effect of antihypertensive drugs on aortic atherogenesis in hypercholesterolemic rabbits. In enalapril and nifedipine treated rabbits aortic atherosclerotic plaque involvement was significantly decreased (p<0. Oland p<O. 05, respectively) as compared to the control group. However, in hydrochlorothiazide treated rabbits aortic atheroge...
متن کاملAntihypertensive drugs and prevention of atherosclerotic stroke.
THE DRAMATIC DECLINE IN STROKE incidence in North America (approximately 60% in the past 15 years) has provoked much debate about the reasons for the decline. The role of the treatment of blood pressure in the reduction of stroke in general, and intracerebral hemorrhage in particular, has been a focus of the debate. Our recent experience highlights the need to pay attention, in future, to those...
متن کاملAntihypertensive effects of some new nitroxyalkyl 1,4-dihydropyridine derivatives in rat model of two-kidney, one-clip hypertension
Dihydropyridine calcium channel blockers consist one of the widely-used groups of drugs for the management of hypertension. In this study, antihypertensive effects of 5 newly synthesized derivatives of DHP was examined the in rat model of two-kidney, one-clip renal hypertension. The results showed that those compounds containing two nitroxy groups had less decreasing effect on MAP (Men Arterial...
متن کاملLOX-1 protein, A Biomarker in the Prognosis of Atherosclerosis
LOX-1 is a class E scavenger receptor that mediates the uptake of oxLDL by vascular cells. LOX-1 is involved in endothelial dysfunctions, monocyte adhesion, the proliferation, migration, and apoptosis of smooth muscle cells, foam cell formation, platelet activation, as well as plaque instability; all of these events are critical in the pathogenesis of atherosclerosis. These LOX-1-dependent bio...
متن کاملInsulin and hypertension: a causal relationship?
The association between insulin and hypertension has been extensively explored during the past decade and remains an area of intense discussion and debate. Interest in the link between insulin and high blood pressure was fueled by two distinct observations: (i) the lack of effective antihypertensive drugs to reduce the increased risk of coronary artery disease in hypertensive subjects [l-4] and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Circulation
دوره 48 5 شماره
صفحات -
تاریخ انتشار 1973